Sunday, July 1, 2012

Can aspirin be still used?

Can aspirin be still used?
Can aspirin be still used?
Peking University first professor of internal medicine of hospital nerve yellow one would rather the intersection of doctor and Liu Ran editor's note enter July, the news related to medicine is coming out one after another constantly. The research that it is scholar relevant aspirin of our country first has boarded magazine of " neurology of lancet ". Research verifies aspirin may cause patient's cerebral hemorrhage, its security is defeated by west Lip river its thiazole. Later, U.S.A. pediatrics learnt to propose, years old and the above children should take and resist cholesterol medicines the part 8 for the first time, suffer from heart disease after in order to prevent it from being grown up. For the knowledge of using medicine behind helping readers to understand news as soon as possible, we invite the relevant domain expert as soon as possible, understand these professional information, is putting out together in this issue. Which knowledge of using medicine correlated to disease if you also want to understand, please contact us. We will do everything possible to ask the authoritative expert to resolve doubts for you. E-mailbox: wangjy8008@163.com The news pegging is taken the lead by the first hospital department of nerve internal medicine in Peking University, the ones that lasts 3 years to finish in domestic over ten hospitals <>, issue on the sixth issue " neurology of lancet " magazine of this year. This result of study reveals, west Lip river its thiazole prevents the result of the apoplexy from being similar to aspirin, but bleed and break out and obviously reduce, security is better. Aspirin is a generally acknowledged standard medicine of apoplexy of prevention, how could cerebral hemorrhage be initiated? A lot of patients can't help asking, should give up aspirin, then choose west Lip river its thiazole to prevent the apoplexy? Chinese's cerebral hemorrhage risk higher brain apoplexy is disease that highly causes death and disables. Until our country have 1,500,000 people die of the intersection of brain and apoplexy nearly every year, second only to of cancer, two die disease roughly. More important, 70% will leave over the deformity at various degrees in the apoplexy survivor, disable the intersection of rate and supreme disease. The apoplexy of brain is because the brain blood vessel stopped up or broke suddenly to cause the brain to organize damaging, will present a series of symptom. We divide him into two big classes of infarction of brain and cerebral hemorrhage. The former more to meet, account for 70%, the latter accounts for 30%. But the proportion of Chinese's cerebral hemorrhage is much higher than western crowd. The classical medicine exposes the prevention of the risk brain apoplexy of bleeding and treats or takes medicine as the core, among them it is most effective to gather medicines in order to resist the blood platelet. Aspirin is the most classical medicine for infarction of prevention and cure brain, oral 75mg 150mg of every day, every 100 people use for one year continuously, can prevent a person from suffering from the apoplexy. Though there are actually few people benefiting, its expenses are cheap, the result is sure, the side effect is small, employed extensively. An unexpected one is, with treating the crowd's increase, the doctor finds some patients not only has not benefited, cause the bad reaction instead, the most serious one is the aspirin relevant cerebral hemorrhage or bleeding of other positions of the health. The incidence of the simple cerebral hemorrhage is in 1.04% to 4.09%. Find 7599 the intersection of patient and during this period observation in 18 months too in the international large-scale clinical the intersection of experiment and MATCH at the same time, the massive haemorrhage which jeopardize the life happen to about 2.6% patients taking aspirin and uniting chlorine pyrrole Grey. Another result of study shows, the bleeding rate that aspirin cause is 1.4% that use separately. Prevent from consumption have best the intersection of choice and a lot of patient and doctor can't help, want, ask can aspirin spend even? Chinese have more cerebral hemorrhage, take may be higher that the chance of cerebral hemorrhage takes place in aspirin, is it more dangerous? In fact, the the intersection of medicine and favorable and the intersection of fraud and two. Aspirin can reduce thrombosis to gather while resisting the blood platelet, thus prevent and treat infarction of brain. It is exactly this function at the same time, causing the thrombus be unable to take shape, cause cerebral hemorrhage. To prevent and cure infarction of brain, one should face the risk of cerebral hemorrhage, this is a double-edged sword. In order to solve this problem, experts have carried on research to existing medicine prescription, dosage, operation method, and is developing new medicine constantly, its purpose is to try hard to produce the therapeutic effect of the medicine, reduce bad function at the same time. A clear one should first be, is aspirin really effective? A large amount of research has already verified, it is effective aspirin and prevents to acute one of infarction of brain for a long time. Acute issue study, reveal definite result their too to big sample Chinese. Secondly it is the comparison of the curative effect of heavy dose of and low dose of aspirin. Prevent cerebrovascular diseases, use aspirin to be smaller than 50mg and come to naught every day, but is greater than 325mg, its result will not increase either, the medicine side effect of bleeding instead etc. obviously increases. Think, the best choice is every day 50mg 150mg to prevent from using medicine at present. It is the question of jointly using medicine again. As stated above, the function of aspirin is very limited. But amalgamating administration can't reduce infarction of brain and take place either, increase the side effect of bleeding instead. Healthy people should not use the clinical discovery of aspirin, some patients use aspirin very effectively, but some patients are apt to bleed. The best method is only using for the effective person, the person apt to bleed does not use. However, some factors determine this kind of difference is unable to find out. According to the clinical experience, we think the following crowds may increase the probability of cerebral hemorrhage to use aspirin: There is no dangerous factor ' Hypertension, diabetes, vascular and narrow, apoplexy medical history,etc.) Healthy people. Prevent from employing aspirin as to these crowds, it is higher than to the probability of the apoplexy of brain happens to present the probability of the bad reaction of bleeding etc. naturally, use aspirin to lose more than gain. Blood pressure is not controlled well, the person who higher thans 180/100mmHg of blood pressure. The nuclear magnetic resonance of brain reveals that there are persons who bleeds some of a plurality of traces in the brain. There have been patients of medical history of a of bleeding under spider's omentums. These patients mustn't use aspirin. There has been the above of half a year, omen symptom of infarction of brain appeared repeatedly recently, if the transient brain is ischemic breaks out, can use aspirin, but very careful. Been already to patients who resists the blood platelet or anticoagulatory medicine such as chlorine pyrrole Grey, China's decree,etc. taking. Person who has gastrorrhagia medical history that allergic medical history of aspirin or aspirin causes. Persons who take antipyrestic of all kinds of acid of the bigcatkin willow at the same time. In a word, aspirin prevents the first-selected medicine for infarction of brain, and is used for acute issues of only effective resisting the blood platelet medicine at present. Have cerebral hemorrhage patient of risk to had better spend little, can choose, resist the blood platelet medicine while being other. Handle this contradiction well, can improve the curative effect of aspirin, reduce the side effect. Each situation of patient different, specifically take aspirin accept main fact Managing the doctor's opinion, the doctor who only understands the patient most has a say. In addition, the patient don't stop medicines at will by oneself, otherwise infarction of brain appears more easily. It is chained that relevant: May west Lip river its thiazole substituted? The wine ��? Besides aspirin, there are the following aspects that resist the blood platelet medicine at being clinical. Pairs of Mi reach, use separately pairs of Mi reach unsatisfactory result, heavy dose of pairs of Mi reach (200mg 400mg) every day Being used in a lot of countries with aspirin jointly is a general first-selected treatment. Unfortunately, one big sample of this year study, reveal the the intersection of operation method and curative effect the intersection of chlorine and pyrrole kind Grey have than use separately, will increase and bleed instead. Chlorine pyrrole Grey is certainly effective when using chlorine pyrrole Grey to prevent infarction of brain for a long time, perhaps better than aspirin. Used mainly in preventing brain infarction of the invalid one of aspirin at present, there are not its assessment materials which treats acute results of infarction of brain yet. In addition, all materials are the research from western crowd, lack Chinese crowd's big sample to observe and study. West Lip river its thiazole, this medicine, uses in the eastern philtrum many. A big sample studies to reveal, long term administration west Lip river its thiazole can prevent infarction of brain effectively in Japan. Our recent research reveals, its result is similar to aspirin at least, cerebral hemorrhage and other bleeding side effects are reduced notably. But can replace aspirin and use extensively, will wait for the verification of the bigger sample. Whether no matter intravenous preparation or oral preparation of saccharified albumen IIb/IIIa receptor inhibitor of blood platelet, it prevents and cures research of infarction of brain, " die young " because of causing more cerebral hemorrhage ,it use for not preventing and curing by brain infarction at it is so clinical. Thrombus plain the intersection of A2 and direct the intersection of inhibitor and long term administration their prevent the intersection of brain and clinical loud sample of infarction, studied and in progress at present, it may be a very promising new medicine.


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