Hong Kong scholar claims to succeed in analysing and explaining foetus' genetic atlas

Hong Kong scholar claims to succeed in analysing and explaining foetus' genetic atlas
Hong Kong scholar claims to succeed in analysing and explaining foetus' genetic atlas
News from China News Agency Hong Kong on December 9 (reporter Roof beam today) Chinese University of Hong Kong claims to succeed in utilizing DNA (DNA) in blood plasma of parent on the 9th Analyse and explain the foetus' genetic atlas, this breakthrough discovery can diagnose foetuses are various hereditary diseases early. Scientific research group which the medical college of Chinese University of Hong Kong, Li Jiacheng healthy chief of scientific research institute Professor Lu YuMing led, succeed in analysing and explaining foetus' genetic atlas in 13 years. Lu YuMing says to the reporter of China News Service, after analysing and explaining foetus' genetic atlas, can be through collecting the pregnant woman's blood plasma sample, cross diagnosing whether foetuses have suffered from various hereditary diseases, " this is a revolutionary discovery once, can with diagnose the foetus' hereditary disease wound nature method for the first time, basically all hereditary diseases can be diagnosed. " Lu YuMing points out, examined the foetus' hereditary disease in the past, the pregnant woman must accept the invading inspection, for example smoke the amniotic fluid, miscarry the risk is about 1%. He says, new DNA inspects technology by random samples to only need to collect a blood plasma sample of pregnant woman, can measure many kinds of hereditary diseases, there is not any risk. However, this technology is not yet ripe, costs about 1,500,000 Hongkong dollars to measure each time, but Lu Yu will point tomorrow, though the cost that involves now is very expensive, will estimate the technological cost will drop fast within several years, it is the quickest can not not 5 year later popularization and application,might take Hongkong dollar of 1 to 20,000 yuan expenses only. Professor Lu YuMing and his scientific research group found the blood plasma memory of the pregnant woman had the foetus' DNA for the first time in 1997. In order to prove the foetus' whole genome really exists in the pregnant woman's blood plasma, the research group that he led has collected a mother's blood plasma, and analyze nearly 4 billion sequencing of the blood plasma DNA, this means human genome of about 65 times. Study group, look for the intersection of foetus and father, have alone in data then, but unexistent sequencing, mother of foetus. In these sequencing, scientific research personnel learn the genetic atlas that foetuses reach from father's heredity. "This task is extremely challenging, because the DNA in the blood plasma is very scrappy. Our work can be compared to finishing one and having several million scenes of jigsaws, " Lu YuMing describes the arduousness of the task so. Account for the intersection of pregnant woman and the intersection of blood plasma and about 1/10 DNA only on the basis of DNA of foetus, want, it surveys foetuses to be more difficult in genetic atlas that heredity reach from mother. However, the middle and big research team develops a new method, see through it from the density of different DNA in the blood plasma, obtained from mother's heredity by foetus which sequencing is inferred, and combine father with mother's genetic atlas, can learn the foetus' genetic atlas, succeed in diagnosing foetuses are persons who carry of anemia of B-mode Mediterranean. But Lu YuMing points out at the same time, because only one mother's body sample tests at present, so accuracy need checking card still. (End)


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