Take precautions against surprise attack of Escherichia coli new mutation
Take precautions against surprise attack of Escherichia coli new mutation
It is reported ' The intersection of reporter and Zheng dexterous) Recently, website, the intersection of Germany and enterorrhagia Escherichia coli (EHEC) website, CDC of U.S.A., CDC of European, The epidemic situation causes pathogenic O104H4 to be called the intestines and produced the will and congratulated Escherichia coli of toxin. For take precautions against intestines produce will congratulate the intersection of toxin and Escherichia coli, recombinate, turn into the new etiology and cause trouble because of the gene moreover, China CDC had already launched the relevant research plan a few days ago. Chief researcher Xu JianGuo claims when being interviewed by staff reporter that China CDC infectious disease prevents and cotrols, existing virulence genetic test and genome array analysis show, enterorrhagia Escherichia coli O104H4 of Germany, it is not in fact real EHEC. It does not have EHEC specific EHEC-hly ' Hemolysin) Gene and EAE virulence island, its genome and enteric gathering genome which stick Escherichia coli are very similar. JianGuo Xu analyze, think O104H4 whether the intersection of intestines and person who gather stick Escherichia coli behind not getting, congratulating toxin 2 phaging by one the intersection of code and will probably, a kind of new pathogen produced. It has superstrong sticking strength to leather cells at the intestine that the intersection of intestines and person who gather stick Escherichia coli; Will congratulate have very strong the intersection of intestines and toxicity, the intersection of cell and toxicity and neural toxicity by 2 toxin, it is apt to cause dissolving courageous and upright urine poisonous syndrome. Such new pathogens evolve from the combination of these two kinds of virulence. Xu JianGuo says, the bacterium can move the hereditary component including plasmid and phage. The plasmid can be through jointing, transforming etc., transmit among the bacteria. The phage can infect the sensitive bacterium, combine into the chromosome. The gene of the wishable toxin 2 of the will is on phage. German incident, O104H4 of Escherichia coli, prove, encode will congratulate the intersection of toxin and 2 phage, rotate and can produce the new pathogen to lead. It is not unique, China CDC infectious disease prevents and cotrols, discovers, caused enterorrhagia Escherichia coli O157H7 breaking out in epidemic situation in the South of our country in 1999 recently, having obtained a plasmid from the sramana fungus, virulence is strengthened. Escherichia coli has more than 170 serum types. Code will congratulate toxin 2 phage, still transfer to what serum type Escherichia coli does it lead? Cause the large area epidemic situation to get rich quick popularly again, OK? These problems all remain to further study. It is reported, China CDC claimed to launch the intestines and produce the will and congratulate Escherichia coli of toxin to further investigate the plan a few days ago, the key content includes: The intestines of our country have the will and congratulate Escherichia coli of toxin to investigate; The intestines have the will and congratulate dealing with technology of Escherichia coli of toxin; Measure, determine, monitor the new method; Prevent the control strategy; Mechanism,etc. happen in new pathogens.
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