The something small and hard of novel cause of disease of lupus erythematosus is announced

The something small and hard of novel cause of disease of lupus erythematosus is announced
The something small and hard of novel cause of disease of lupus erythematosus is announced
It is reported ' Reporter Li TianShu) The joint study that the research institute of Shanghai life of Chinese Academy of Sciences and subsidiary researcher of Yan Chai Hospital of Shanghai Communications University carry on is announced, patient miR-125a gene expression defect of lupus erythematosus, this discovery regards this gene as a new medicine and intervenes the target to click, it is expected to become the new means of lupus erythematosus treatment. Lupus erythematosus is that one involves multi system many organs of body, clinical manifestation is complicated, the course of disease delays repeated one's own immune disease. In recent years, the healthy scientific research institute of research institute of Shanghai life of Chinese Academy of Sciences cooperates with Shanghai Communications University subsidiary rheumatism dept. of Yan Chai Hospital, tackle key problems to the basic research field of lupus erythematosus. Researchers found a few days ago, in lupus erythematosus patient's peripheral blood T cells, the level of miR-125a was obviously lower than normal people. The research points out the patient miR-125a gene expression defect of the lupus, may be that it trends towards and melts albumens(RANTES) in the body One of the unusually raised reasons, and expected to intervene the target to click as a new medicine. Researchers pointed out, human disease often because some gene expression is adjusted and controlled to cause disorderlily. Some important gene expression adjusts and controls the factor, the emergence in the human disease plays an important role while developing. This research results are published on magazine of " arthritis and rheumatism ".


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